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Test Code HBSQAB Hepatitis B Surface Antibody [LAB3480]

Test Method

Chemiluminescent immunoassay (sandwich principle); Roche cobas Pro

Performance

Testing is performed 7 days a week Monday through Sunday.

Routine requests are completed the same day once received at the laboratory.

Stat requests are completed within 4 hours of receipt at the laboratory. 

Useful For

Anti‑HBs is an antibody that is directed against the hepatitis B surface antigen. Anti‑HBs can be formed following a hepatitis B infection or after hepatitis B vaccination. Antibodies are formed against the HBsAg determinant a, which is common to all subtypes, and against subtype‑specific determinants. 

Anti‑HBs tests are used within the scope of hepatitis B vaccination to check the necessity and success of vaccination. In addition, anti‑HBs tests are used to monitor the course of disease following acute hepatitis B infection. The Elecsys Anti‑HBs assay uses a mixture of purified antigens of the HBsAg subtypes ad and ay from human serum.

Reference Values

Anti-HBs II Result Result Interpretation Clinical Interpretation of HBV Immune Status
< 10 mIU/mL Non-reactive Individual is considered to be not immune to infection with HBV.
≥ 10 mIU/mL Reactive Anti-HBs concentration detected at ≥ 10 mIU/mL. Individual is considered to be immune to infection with HBV.

Performing Laboratory

UnityPoint Finley Hospital

Specimen Requirements

  1. Serum is the specimen of choice. Gel tubes are acceptable. (Red top or Gold top).
  2. EDTA plasma is also acceptable. (Purple top)
  3. Serum samples for Hepatitis B Antibody specimens are stable for up to 8 hours at 20-25°C, 6 days at 2-8°C, and 3 months at -20°C.
  4. EDTA plasma samples for Hepatitis B Antibody are stable for up to 8 hours at 20-25°C, 2 days at 2-8°C, and 3 months at -20°C. 

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