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Test Code UTPCRR Total Protein Creatinine Ratio Urine, Random LAB743

Test Method

Protein: Dye-Binding Colorimetric Method; Beckman DXC600
Creatinine: Jaffe Rate; Beckman


Testing is performed Monday through Sunday

Typically completed the same day the specimen arrives at the
testing site.

Useful For

The total protein to creatinine ratio estimates the degree of
proteinuria based on a single random urine collection. Increased
amounts of protein in the urine may be seen with glomerular
disease, over-flow proteinuria, urinary tract inflammation and
urinary tract neoplasm. While the total protein/creatinine ratio
can be used for screening or monitoring proteinuria in certain
clinical situations, the 24 hour urine total collection remains the
test of choice to measure true proteinuria.

Specimen Requirement

2 mL urine is required.

CPT Code Information

84156 Chemistry: Protein, total, except by refractometry,

82570 Chemistry: Creatinine; other source

Reference Values


Reference value not established for children <2 years of

LOINC Code Information

2890-2 Protein/Creatinine [Mass Ratio] In Urine

Additional Specimen Collection Information

Random urine specimens should be collected in a plastic
container.  No preservative required. Label the specimen
appropriately with two identifiers, patient name and another
identifier, (patient ID number, DOB, etc.) include date and time of
collection. Urine specimens should be assayed within two hours
of collection. If a urine cannot be run within two hours store
refrigerated for up to 72 hours. Frozen samples are not


Do not place specimen in a glass container. Do not collect
specimens from patients with a urinary tract infection. Urine
should not be collected during periods of exercise or prolonged
upright posture. Avoid hematuria or blood contamination.