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Test Code MSQUAD AFP Maternal Quad Screen

Important Note

***Grant Regional users: Please refer to test code QUADM Quad Scrn (2nd Tri) Maternal, Serum.***

Additional Codes

Epic: LAB2270

Performance

Testing is performed Monday through Sunday.

Specimen Requirement

2 mL serum is required.

Useful For

Detection of fetal abnormalities due to birth defects or chromosome abnomalities

Reference Values

The Maternal Quad Screen is the second stage screening test for Down’s Syndrome, Trisome 18 and Open Neural Tube Defects. Alpha Fetoprotein (AFP), Estriol, Human Chorionic Gonadotropin (hCG) and Inhibin are reported. Also included are the risk assessment for age related Down’s Syndrome, Down’s Syndrome and Trisomy 18. An interpretation and recommended action are included.

LOINC Code Information

49085-4 First and Second Trimester Integrated Maternal Screen Panel

Method

Quantitative Chemiluminescent Immunoassay

Additional Specimen Collection Instructions

Blood:

  1. Collect blood in a plain, red-top tube(s) or serum gel tube(s).
  2. Allow the blood to clot, then centrifuge and remove serum (at least 2 ml) from the tube and transfer to a tube labeled with patient name or unique identifier and date of birth.
  3. Wrap the tube in absorbent material and place in a biohazard bag.
  4. Keep specimen refrigerated until ready for CDS pick up.
  5. Unlabeled specimens will not be tested.
  6. Send along with the completed Iowa Maternal Screen Test Request form.
  7. The specimen must be received by SHL within 9 days of collection date.

CPT Information

82105 Chemistry: Alpha-fetoprotein (AFP); serum

82677 Chemistry: Estriol

84702 Other and Unlisted Chemistry Tests: Conadotropin, chorionic (hCG); quantitative

86336 Diagnostic Immunology: Inhibin A