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Test Code LEVET Levetiracetam (Keppra)

Additional Codes

EPIC: LAB477

Performing Laboratory

Pathology Laboratory Des Moines, IA

Clinical Testing | Pathology Laboratory

Performance

Performed: 

Monday-Friday 8:00a to 10:00p
Saturday-Sunday 9:00a to 5:00p

 

Analytical Time: 

2 hours

Methodology

Immunoassay

This levetiracetam (Keppra) immunoassay uses the ARK Diagnostics reagents, which has known cross-reactivity with the drug brivaracetam (Briviact) and may report inaccurate results. Patients transitioning from levetiracetam to brivaracetam or those who are using both medications should not monitor drug concentrations with the ARK Diagnostics assay. These patients should be monitored using a validated chromatographic methodology that distinguishes between drugs to determine drug concentrations.

Specimen Requirement

Preferred Collection Container: 

Red (No Additive)

 

Also Acceptable Collection Container: 

Green No Gel (Lithium Heparin)
Lavender (EDTA)

 

Collection Information: 

Serum (Red top) or plasma (Green or Lavender top). For consistency, using the same specimen matrix for individual patients is a good practice.  

Gel separator tubes are NOT acceptable.

 

 

Transport Information: 

3.0 mL blood

 

Minimum Sample Volume: 

0.5 mL of blood (0.1 mL serum or plasma)

 

Unacceptable Conditions: 

Gel separator tubes.

Specimen Stability

Refrigerated Stability: 

7 days

 

Frozen Stability: 

4 weeks

 

Ambient Stability: 

Acceptable if sample has been separated from cells.

CPT Code Information

80177