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Test Code LDH Lactate Dehydrogenase (LD) LAB96

Performing Laboratory

UnityPoint The Finley Hospital

Test Method

Enzymatic Rate Method; Roche cobas Pro

Performance

Testing is performed Monday through Sunday.

Routine: Typically completed within 4 hours after the specimen arrives at the testing site.

STAT: Typically completed within 30 minutes after the specimen arrives at the testing site.

Specimen Requirement

  1. Lithium heparin plasma (green) is the specimen of choice. 500μL.
  2. Serum (red/gold) is also an acceptable sample type.
  3. It is recommended that the serum or plasma be separated from contact with cells within 2 hours from time of collection.
  4. LD Specimens are stable for 7 days at 15-25C. Do not refrigerate. 

Useful For

The lactate dehydrogenase (LDH) enzyme is widely distributed in tissue, particularly in the heart, liver, muscles and kidneys. The LDH in serum can be separated into five different isoenzymes based on their electrophoretic mobility. 

Elevated serum levels of LDH have been observed in a variety of disease states. The highest levels are seen in patients with megaloblastic anemia, disseminated carcinoma and shock. Moderate increases occur in muscular disorders, nephrotic syndrome and cirrhosis. Mild increases in LDH activity have been reported in cases of myocardial or pulmonary infarction, leukemia, hemolytic anemia and non‑viral hepatitis.

Reference Values

< 251 U/L

CPT Code Information

83615 Chemistry: Lactate dehydrogenase (LD,) (LDH)

LOINC Code Information

2532-0 Lactate Dehydrogenase [Enzymatic Activity/Volume] In
Serum Or Plasma