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Test Code HCGQNT Beta-hCG Quantitative, Serum LAB143

Important Note

Human anti-mouse antibodies (hama) may be present in samples from patients who have received immunotherapy or diagnostic procedures utilizing monoclonal antibodies or in individuals who have been regularly exposed to animals. Additionally, other heterophile antibodies, such as human anti-goat antibodies may be present in patient samples. Manufacturers formulate assays to minimize the effects of these antibodies; however careful evaluation of patient results must be done when patients are known to have such antibodies.

Test Method

Immunoenzymatic (“Sandwich”) Immunoassay; Beckman Access II


Specimen Requirement

0.5 mL serum or plasma is required.

Additional Specimen Collection Information

Collect blood in a lithium heparin, green-top or red-top tube.
PST and SST (gel tubes) are acceptable. Serum or plasma should be
separated from contact with the cells within 2 hours of collection.
Specimens not centrifuged within 4 hours of collection may be
rejected. Refrigerate the specimen if unable to assay within 8
hours of collection.

Reference Values


  • Nonpregnant: < 3 mIU/mL 

    hCG results between 5 mIU/mL  and 25 mIU/mL  may be
    indicative of early pregnancy but should be interpreted in light of
    the total clinical presentation of the patient.
  • Pregnant:
    wk 1:<50  mIU/mL
    wk 2:<500  mIU/mL
    wk 3:<5,000  mIU/mL
    wk 4:<10,000  mIU/mL
    wk 5:<50,000  mIU/mL
    wk 6:<100,000  mIU/mL
    wk 8:<200,000  mIU/mL 
    wk 12:<100,000  mIU/mL
    Post Partum: Negative within 2 weeks
  • Healthy non-pregnant peri and post-menopausal females may have
    hCG values up to 10 mIU/mL

Males: <3 mIU/mL


Testing is performed Monday through Sunday.

Routine orders: Typically completed within 4 hours after
specimen arrives at the testing site.

STAT orders: Typically completed within 1 hour after the
specimen arrives at the testing site.

Useful For

Monitoring patients for retained products of conception.

Aid in the diagnosis of gestational trophoblastic disease (GTD),
testicular tumors, ovarian germ cell tumors, teratomas, and,
rarely, other human chorionic gonadotropin (hCG)-secreting


Serial measurement of hCG following treatment to:

-Monitor therapeutic response in GTD or in hCG-secreting

-Detect persistent or recurrent GTD or hCG-secreting tumors


LOINC Code Information

21198-7 Choriogonadotropin.Beta Subunit [Units/Volume] In Serum
Or Plasma

CPT Code Information

84702 Other Unlisted Chemistry Tests:
Gonadotropin, chorionic (hCG); quantitative