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Test Code EBVBAT EPSTEIN-BARR VIRUS ANTIBODY PROFILE [LAB5480]

Performing Laboratory

Pathology Laboratory Des Moines, IA

Clinical Testing | Pathology Laboratory

Performance

Analytical Time: 

1 day

Specimen Requirement

Container/Tube Type: 

Red (No Additive)
SST (Serum Separator)
Green (Lithium Heparin)
Mint Green (Plasma Separator)

 

Transport Information: 

Spin down and send 1 mL of serum refrigerated.

 

Minimum Sample Volume: 

0.25 mL

 

Unacceptable Conditions: 

Gross Hemolysis

CPT Code Information

86664/EBNA; 86665/x2 VCA, IgG & IgM

Specimen Stability

Refrigerated Stability: 

7 days

 

Frozen Stability: 

Indefinitely

Alias

Anti EBV Serology, E. B. (Epstein-Barr) Virus, EBNA (Epstein-Barr Nuclear Antigen), EBV (Epstein-Barr Virus) Battery, EBV (Epstein-Barr Virus) Panel, EBV (Epstein-Barr Virus), EBV Panel, Serum, Epstein Barr Virus, Epstein-Barr Virus AB, Epstein-Barr Virus Battery, Epstein-Barr Virus Panel, VCA (Viral Capsid Antigen) IgG and IgM, Viral Capsid Antigen (VCA) Titer, Infectious Mononucleosis, EBV Ab, Serum

Methodology

Multiplex Flow Immunoassay (MFI)

Interpretative Data

Antibody Timing of when the antibody is typically detected in the blood
Viral Capsid Antigen (VCA)-IgM antibody Appears first after exposure to the virus and then tends to disappear after about 4 to 6 weeks
VCA-IgG antibody Emerges during acute infection with the highest level at 2 to 4 weeks, then drops slightly, stabilizes, and is present for life
Early Antigen (EA-D) antibody Appears during the acute infection phase and then tends to disappear; about 20% of those infected will continue to have detectable quantities for several years after the EBV infection has resolved.
Epstein-Barr Nuclear Antigen (EBNA) antibody Does not usually appear until the acute infection has resolved; it develops about 2 to 4 months after the initial infection and is then is present for life.