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Test Code DHEASI Dehydroepiandrosterone Sulfate (DHEA-S), Plasma or Serum, LAB524

Methodology

Immunoenzymatic Chemiluminescent Assay

Performing Laboratory

St. Luke's Hospital Laboratory, Cedar Rapids

Specimen Requirements

Container/Tube:

Preferred:  Green tube-Lithium Heparin

Acceptable: Red-top serum tube, Lavender-top (EDTA) tube(s) or Gold Tube-SST
Specimen: 0.5 mL

Minimum Volume: 0.09 plus a dead volume 
 

Stability(when removed from cells):

  • Room Temperature:  5 days
  • Refrigerated:  14 days
  • Frozen:  12 months at -20° Celsius.  Freeze only once.

Transport Temperature: Refrigerate

 

Note:  This assay is affected by biotin interference.

 

Reference Values

 

Age Males Females
< 1 week 108 - 607 ug/dL 108 - 607 ug/dL
1 - 4 weeks 32 - 431 ug/dL 32 - 431 ug/dL
1 - 12 months 3 - 124 ug/dL 3 - 124 ug/dL
1 - 4 years 0 - 19 ug/dL 0 - 19 ug/dL
5 - 9 years 3 - 85 ug/dL 3 - 85 ug/dL
10 - 14 years 24 - 247 ug/dL 34 - 280 ug/dL
15 - 19 years 70 - 492 ug/dL 65 - 368 ug/dL
20 - 24 years 211 - 492 ug/dL 148 - 407 ug/dL
25 - 34 years 160 - 449 ug/dL 99 - 340 ug/dL
35 - 44 years 89 - 427 ug/dL 61 - 337 ug/dL
45 - 54 years 44 - 331 ug/dL 35 - 256 ug/dL
55 - 64 years 52 - 295 ug/dL 19 - 205 ug/dL
65 - 74 years 34 - 249 ug/dL 9 - 246 ug/dL

≥ 75 years

 16 - 123 ug/dL 12 - 154 ug/dL

 

Day(s) Test Set Up

Monday-Sunday

Test Classification and CPT Coding

82627

Useful For

Measurement of circulating levels of Dehydroepiandrosterone sulfate (DHEAS), an adrenal steroid, is important in investigations of abnormal hair growth (hirsutism) and balding (alopecia) in women.  It is also of value in the assessment of adrenarche and delayed puberty.  DHEAS in circulation originates almost entirely from the adrenals, though in men some may also derive from the testes.  Although DHEAS is weakly androgenic, it can metabolize to more potent androgens like androstenedione and testosterone, and thus be an indirect cause of hirsutism or virilization.

Analytic Time

Stat 1 hr within receipt

Routine 2 hrs within receipt