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Test Code DHEASI Dehydroepiandrosterone Sulfate (DHEA-S), Plasma or Serum, LAB524

Methodology

Immunoenzymatic Chemiluminescent Assay

Performing Laboratory

St. Luke's Hospital Laboratory, Cedar Rapids

Specimen Requirements

Container/Tube:

Preferred:  Green tube-Lithium Heparin

Acceptable: Red-top serum tube, Lavender-top (EDTA) tube(s) or Gold Tube-SST
Specimen: 0.5 mL

Minimum Volume: 0.09 plus a dead volume 
 

Stability(when removed from cells):

  • Room Temperature:  5 days
  • Refrigerated:  14 days
  • Frozen:  12 months at -20° Celsius.  Freeze only once.

Transport Temperature: Refrigerate

 

Note:  This assay is affected by biotin interference.

 

Reference Values

 

Females

12.0-407 µg/dL

Males

16.2-492 µg/dL

 

Day(s) Test Set Up

Monday-Sunday

Test Classification and CPT Coding

82627

Useful For

Measurement of circulating levels of Dehydroepiandrosterone sulfate (DHEAS), an adrenal steroid, is important in investigations of abnormal hair growth (hirsutism) and balding (alopecia) in women.  It is also of value in the assessment of adrenarche and delayed puberty.  DHEAS in circulation originates almost entirely from the adrenals, though in men some may also derive from the testes.  Although DHEAS is weakly androgenic, it can metabolize to more potent androgens like androstenedione and testosterone, and thus be an indirect cause of hirsutism or virilization.

Analytic Time

Stat 1 hr within receipt

Routine 2 hrs within receipt