Test Code BETA2M Beta-2 Transferrin: Detection of Spinal Fluid in Other Body Fluid
Additional Codes
MAYO: BETA2
EPIC: LAB205
Reporting Name
Beta-2 Transferrin, BFUseful For
Detection of spinal fluid in body fluids, such as ear or nasal fluid
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
Body FluidAdditional Testing Requirements
If specimens are collected from multiple sites on the body (ie, left and right), each specimen must be sent under a separate order.
Necessary Information
Indicate specimen source. Include whether the source is from the right or left side of the body, if applicable.
Specimen Required
Specimen Type: Body fluid
Sources: Nasal, otic, wound, etc
Container/Tube:
Preferred: Sterile container, syringe, test tube, or microtube
Acceptable: Plain cotton swab or gauze
Specimen Volume: 0.5 mL
Collection Instructions:
1. If submitting a syringe, remove needle. Add cap to end of syringe.
2. If direct collection is not feasible, specimen may be collected using a plain cotton swab or gauze.
3. If gauze is used to collect specimen, circle area on the gauze where specimen was collected.
4. Place cotton swab or gauze in as small a container as possible (eg, plain test tube or collection container).
5. Do not collect specimen with a culture swab.
6. Do not add any liquid to the swab or gauze.
Additional Information:
1. Specimens collected from above the shoulders risk salivary contamination, which can degrade the beta-2 transferrin protein. These specimens should be frozen immediately following collection and kept frozen until testing is performed.
2. Although results may be obtainable on smaller specimens (perhaps as little as 0.05 mL, depending on the protein concentrations and percentage of spinal fluid in the specimen), reliable results are best obtained with an adequate specimen volume.
3. Specimens collected with additives such as microbiology media (eg, Stuart or Amies liquid medium) or TransFix/EDTA (used for analyses in flow cytometry) yield uninterpretable results and will be rejected.
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Body Fluid | Frozen | 14 days |
Reference Values
Negative, no beta-2 transferrin (spinal fluid) detected
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86335
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
BETA2 | Beta-2 Transferrin, BF | 13876-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
80351 | Beta-2 Transferrin, BF | 13876-8 |
Report Available
1 to 3 daysMethod Name
Electrophoresis/Immunofixation