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HelpTest Code UALDOM Aldosterone, 24 Hour, Urine
Additional Codes
MAYO: ALDU
EPIC: LAB354
Reporting Name
Aldosterone, UUseful For
Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineAdvisory Information
Advice on stimulation or suppression tests is available from Mayo Clinic's Division of Endocrinology; call 800-533-1710.
Necessary Information
24-Hour volume is required.
Specimen Required
Patient Preparation: If the patient is taking spironolactone (Aldactone), it should be discontinued for 4 to 6 weeks before specimen collection.
Supplies: Urine tubes, 10-mL (T068)
Container/Tube: Plastic, urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Add 25 mL of 50% acetic acid as preservative at start of collection. Use 15 mL of 50% acetic acid for children under the age of 5 years. This preservative is intended to achieve a pH of between approximately 2 and 4.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens and Renin-Aldosterone Studies for more detailed instructions in Special Instructions.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 14 days |
Special Instructions
Reference Values
0-30 days: 0.7-11.0 mcg/24 hours*
31 days-11 months: 0.7-22.0 mcg/24 hours*
≥1 year: 2.0-20.0 mcg/24 hours
*Loeuille GA, Racadot A, Vasseur P, Vandewalle B: Blood and urinary aldosterone levels in normal neonates, infants and children. Pediatrie 1981;36:335-344
For SI unit Reference Values, see https://www.mayocliniclabs.com/order-tests/si-unit-conversion.html
Day(s) and Time(s) Performed
Tuesday, Thursday; 1 p.m.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82088
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ALDU | Aldosterone, U | 1765-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8556 | Aldosterone, U | 1765-7 |
| TM47 | Collection Duration | 13362-9 |
| VL45 | Urine Volume | 3167-4 |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)