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Test Code THYTMM Thyroglobulin, Tumor Marker, Serum

Additional Codes



Useful For

Follow-up of patients with differentiated thyroid cancers after thyroidectomy and radioactive iodine ablation

Testing Algorithm

All specimens are screened for the presence of autoantibodies to thyroglobulin.

Reporting Name

Thyroglobulin, Tumor Marker

Specimen Type

Serum Red

Advisory Information

Refer to TGMS / Thyroglobulin Mass Spectrometry, Serum for accurate sample analysis of patients who are known to be thyroglobulin antibody positive.

Specimen Required

Patient Preparation: For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Collection Container/Tube: Red top (serum gel tubes are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 7 days
  Frozen  30 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Reference Values


Athyrotic: <0.1 ng/mL

Intact thyroid ≤33 ng/mL



<1.8 IU/mL

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday through Friday; 6 a.m.-12 a.m.

Saturday; 6 a.m.-6 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84432-Thyroglobulin, tumor marker

86800-Thyroglobulin antibody screen

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HTG2 Thyroglobulin, Tumor Marker 57780-9


Result ID Test Result Name Result LOINC Value
TGAB2 Thyroglobulin Antibody, S 56536-6
HTGN2 Thyroglobulin, Tumor Marker, S 3013-0
HTG2I Thyroglobulin Interpretation 69053-7

Method Name

Immunoenzymatic Assay


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Oncology Test Request (T729)