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HelpTest Code OPATUM Opiates Confirmation, Random, Urine
Additional Codes
MAYO: OPATU
EPIC: LAB5401
Reporting Name
Opiate Confirmation, UUseful For
Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineAdvisory Information
1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order OPATX / Opiates Confirmation, Chain of Custody, Urine.
2. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Urine.
Specimen Required
Supplies: Aliquot Tube, 5 mL (T465)
Collection Container/Tube: Plastic urine container
Submission Container/Tube: Plastic, 5-mL tube
Specimen Volume: 3 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Specimen Minimum Volume
2.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 14 days |
Reference Values
Negative
Cutoff concentrations
Codeine by LC-MS/MS: 25 ng/mL
Dihydrocodeine-by LC-MS/MS: 25 ng/mL
Hydrocodone by LC-MS/MS: 25 ng/mL
Norhydrocodone-by LC-MS/MS: 25 ng/mL
Hydromorphone by LC-MS/MS: 25 ng/mL
Oxycodone by LC-MS/MS: 25 ng/mL
Noroxycodone-by LC-MS/MS: 25 ng/mL
Oxymorphone by LC-MS/MS: 25 ng/mL
Noroxymorphone-by LC-MS/MS: 25 ng/mL
Naloxone-by LC-MS/MS: 25 ng/mL
Morphine by LC-MS/MS: 25 ng/mL
Day(s) and Time(s) Performed
Monday through Friday; Varies
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80361
80365
80362
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| OPATU | Opiate Confirmation, U | 74760-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 6543 | Codeine-by LC-MS/MS | 16250-3 |
| 42000 | Dihydrocodeine-by LC-MS/MS | 19448-0 |
| 21177 | Hydrocodone-by LC-MS/MS | 16252-9 |
| 42001 | Norhydrocodone-by LC-MS/MS | 61422-2 |
| 21179 | Hydromorphone-by LC-MS/MS | 16998-7 |
| 21178 | Oxycodone-by LC-MS/MS | 16249-5 |
| 42002 | Noroxycodone-by LC-MS/MS | 61425-5 |
| 35023 | Oxymorphone-by LC-MS/MS | 17395-5 |
| 42003 | Noroxymorphone-by LC-MS/MS | 90894-7 |
| 42004 | Naloxone-by LC-MS/MS | 77207-9 |
| 6542 | Morphine-by LC-MS/MS | 16251-1 |
| 21180 | Opiates Interpretation | 18390-5 |
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.