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Test Code MMAUM Methylmalonic Acid, Quantitative, Urine

Additional Codes



Reporting Name

Methylmalonic Acid, QN, U

Useful For

Evaluating children with signs and symptoms of methylmalonic acidemia using urine specimens


Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type


Specimen Required

Patient Preparation: Overnight fast required

Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 4 mL

Collection Instructions: Collect second-voided specimen after an overnight fast.

Specimen Minimum Volume

1.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen (preferred) 28 days
  Refrigerated  28 days
  Ambient  21 days

Reference Values

<3.60 mmol/mol creatinine

Day(s) Performed

Monday through Friday

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
MMAU Methylmalonic Acid, QN, U 25116-5


Result ID Test Result Name Result LOINC Value
80290 Methylmalonic Acid, QN, U 25116-5

Report Available

3 to 5 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Biochemical Genetics Test Request (T798)

-Benign Hematology Test Request (T755)