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HelpTest Code MDNS Methadone and Metabolites, Serum
Additional Codes
MAYO: MDNS
EPIC: LAB1054
Useful For
Compliance monitoring of methadone
Assessment of methadone toxicity
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Methadone and Metabolite, SSpecimen Type
Serum RedSpecimen Required
Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days | |
| Ambient | 14 days | ||
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Not established
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80358
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MDNS | Methadone and Metabolite, S | 96602-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 36309 | Methadone | 3772-1 |
| 36310 | EDDP | 60071-8 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.