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HelpTest Code HMU24M Heavy Metals Screen, with Reflex, 24 Hour, Urine
Additional Codes
MAYO: HMU24
EPIC: LAB398
Specimen Required
Patient Preparation:
1. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
2. Patient should not eat seafood for a 48-hour period prior to start of, or during, collection.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic aliquot container with no metal cap or glued insert
Submission Container/Tube: Plastic, 10-mL urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
3. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.
Secondary ID
48538Useful For
Detecting arsenic, cadmium, mercury, and lead exposure and toxicity using 24-hour urine specimen
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ASHU | Arsenic, 24 Hr, U | Yes, (order ASU24) | Yes |
| CDHMU | Cadmium, 24 Hr, U | Yes, (order CDU) | Yes |
| HGHU | Mercury, 24 Hr, U | Yes, (order HGU) | Yes |
| PBHU | Lead, 24 Hr, U | Yes, (order PBU) | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| SPASU | Arsenic Speciation, 24 Hr, U | Yes | No |
Testing Algorithm
If arsenic concentration is greater than or equal to 10 mcg/L, then speciation will be performed at an additional charge.
Special Instructions
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Reporting Name
Heavy Metal Scrn w/Reflex, 24 Hr, USpecimen Type
UrineSpecimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 7 days | |
| Frozen | 7 days |
Reject Due To
| All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
ARSENIC:
0-17 years: not established
≥18 years: <35 mcg/24 hour
CADMIUM:
0-17 years: not established
≥18 years: <0.7mcg/24 hour
MERCURY:
0-17 years: not established
≥18 years: <2 mcg/24 hour
Toxic concentration: >50 mcg/24 hour
The concentration at which toxicity is expressed is widely variable between patients.
50 mcg/24 hour is the lowest concentration at which toxicity is usually apparent.
LEAD:
0-17 years: not established
≥18 years: <2 mcg/24 hour
Day(s) and Time(s) Performed
Monday through Saturday; 7 p.m.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82175
82300
83825
83655
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HMU24 | Heavy Metal Scrn w/Reflex, 24 Hr, U | 94575-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8678 | Cadmium, 24 Hr, U | 5612-7 |
| 48539 | Arsenic, 24 Hr, U | 5587-1 |
| 92408 | Mercury, 24 Hr, U | 6693-6 |
| 92409 | Lead, 24 Hr, U | 5677-0 |
| TIME4 | Collection Duration | 13362-9 |
| 92215 | Total Arsenic Concentration | 21074-0 |
| VL16 | Total Volume | 3167-4 |