Test Code HMU24M Heavy Metals Screen, with Reflex, 24 Hour, Urine
Additional Codes
MAYO: HMU24
EPIC: LAB398
Specimen Required
Patient Preparation:
1. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
2. Patient should not eat seafood for a 48-hour period prior to start of, or during, collection.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic aliquot container with no metal cap or glued insert
Submission Container/Tube: Plastic, 10-mL urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
3. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.
Secondary ID
48538Useful For
Detecting arsenic, cadmium, mercury, and lead exposure and toxicity using 24-hour urine specimen
Profile Information
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
ASHU | Arsenic, 24 Hr, U | Yes, (order ASU24) | Yes |
CDHMU | Cadmium, 24 Hr, U | Yes, (order CDU) | Yes |
HGHU | Mercury, 24 Hr, U | Yes, (order HGU) | Yes |
PBHU | Lead, 24 Hr, U | Yes, (order PBU) | Yes |
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
SPASU | Arsenic Speciation, 24 Hr, U | Yes | No |
Testing Algorithm
If arsenic concentration is greater than or equal to 10 mcg/L, then speciation will be performed at an additional charge.
Special Instructions
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Reporting Name
Heavy Metal Scrn w/Reflex, 24 Hr, USpecimen Type
UrineSpecimen Minimum Volume
3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 7 days | |
Frozen | 7 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
ARSENIC:
0-17 years: not established
≥18 years: <35 mcg/24 hour
CADMIUM:
0-17 years: not established
≥18 years: <0.7mcg/24 hour
MERCURY:
0-17 years: not established
≥18 years: <2 mcg/24 hour
Toxic concentration: >50 mcg/24 hour
The concentration at which toxicity is expressed is widely variable between patients.
50 mcg/24 hour is the lowest concentration at which toxicity is usually apparent.
LEAD:
0-17 years: not established
≥18 years: <2 mcg/24 hour
Day(s) and Time(s) Performed
Monday through Saturday; 7 p.m.
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82175
82300
83825
83655
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
HMU24 | Heavy Metal Scrn w/Reflex, 24 Hr, U | 94575-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8678 | Cadmium, 24 Hr, U | 5612-7 |
48539 | Arsenic, 24 Hr, U | 5587-1 |
92408 | Mercury, 24 Hr, U | 6693-6 |
92409 | Lead, 24 Hr, U | 5677-0 |
TIME4 | Collection Duration | 13362-9 |
92215 | Total Arsenic Concentration | 21074-0 |
VL16 | Total Volume | 3167-4 |