Test Code COKEMM Cocaine and Metabolites Confirmation, Meconium
Additional Codes
MAYO: COKEM
EPIC: LAB5305
Reporting Name
Cocaine and Metabolites, Confirm, MUseful For
Detecting in utero drug exposure up to 5 months before birth
Performing Laboratory

Specimen Type
MeconiumOrdering Guidance
For chain-of-custody testing, order COKMX / Cocaine and Metabolite Confirmation, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container, Small (Random), 4 oz (T288)
Container/Tube: Stool container
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Specimen Minimum Volume
0.3 g (approximately 1/4 teaspoon)
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Meconium | Frozen (preferred) | 21 days |
Refrigerated | 21 days | |
Ambient | 72 hours |
Reference Values
Negative
Positives are reported with a quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) result.
Cutoff concentrations for LC-MS/MS testing:
Cocaine: 20 ng/g
Benzoylecgonine: 20 ng/g
Cocaethylene: 20 ng/g
m-Hydroxybenzoylecgonine: 20 ng/g
Day(s) Performed
Monday through Sunday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
G0480
80353 (if appropriate for select payers)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
COKEM | Cocaine and Metabolites, Confirm, M | 69008-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
31859 | Cocaine | 69009-9 |
31860 | Benzoylecgonine | 69010-7 |
31861 | Cocaethylene | 69011-5 |
31862 | m-Hydroxybenzoylecgonine | 69012-3 |
31864 | Interpretation | 69050-3 |
31865 | Chain of Custody | 77202-0 |
Report Available
2 to 3 daysReject Due To
Grossly bloody | Reject; Pink OK |
Stool Diapers |
Reject |
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.