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Test Code ABSCR Antibody Screen LAB278

Test Method

AABB Standard: Agglutination of red cells with an antiserum
represents the presence of the corresponding antigen in the red
cells; Ortho Gel Cards. (AABB Technical manual. 14th edition.
Edited by V Vengelen-Tyler. Bethesda, MD, American Association of
Blood Banks 2002)

 

Performance

Testing is performed Monday through Sunday.

Routine: Typically completed within 4 hours after the
specimen arrives at the testing site.

Expedite: Typically completed within 1 hour after the specimen
arrives at the testing site.

STAT: Typically completed within 45 minutes after the specimen
arrives at the testing site.

Specimen Requirement

A 5 mL EDTA purple-top tube is preferred.

Useful For

Detection of allo- or autoantibodies directed against red blood
cell antigens in the settings of pretransfusion testing.

Evaluation of transfusion reactions.

Evaluation of hemolytic anemia.

Reference Values

Negative

CPT Code Information

86850 Antibody Screen, RBC, each serum technique.

LOINC Code Information

14575-5 Blood Group Antibody Investigation [Interpretation] In
Plasma Or RBC

Additional Specimen Collection Information

7 mL red-top, 5 mL heparin green-top or 5 mL blue-top tubes are
also acceptable. Serum and plasma gel tubes are not acceptable.

Testing Algorithm

If the antibody screen is positive, then antibody identification
will be performed.

The following tests may also be ordered and performed as part of
antibody identification: monospecific direct Coombs, special red
cell antigen typing, antibody elution, and antibody absorption.