Test Code THEO Theophylline (Aminophylline) LAB35
Test Method
Turbidimetric Inhibition Immunoassay; Beckman DXC600
Specimen Requirement
0.5 mL serum or plasma is required.
Additional Specimen Collection Information
Collect blood in a lithium heparin, green-top or red-top
tube.
Serum and plasma gel tubes are not acceptable.
- Suspected toxicity specimens are collected when symptoms
appear. - Acute therapy specimens are collected 30 minutes following
I.V.
loading dose and again at 4-8 hour intervals. - Peak specimens should be collected at least 2 hours
after
last dose for plain uncoated tablet and liquids; 4 hours after oral
dose for sustained release prducts.
Serum or plasma should be separated from contact with the
cells
within 2 hours of collection. Specimens not centrifuged within
4
hours of collection may be rejected. Refrigerate the specimen
if
unable to assay within 8 hours of collection. Samples with
>3+
lipemia must be cleared prior to analysis.
Reference Values
Therapeutic: 8-20 mcg/mL
-
Critical Value: > 20 mcg/mL
Performance
Monday through Sunday
Routine: Typically completed within 4 hours after arrival at
the
testing site.
Expedite: Typically completed within 1 hour after
specimen
arrives at the testing site.
STAT: Typically completed within 30 minutes after specimen
arrives at the testing site.
Useful For
Assessing and adjusting dosage for optimal therapeutic level
Assessing toxicity
LOINC Code Information
4049-3 Theophylline [Mass/Volume] In Serum Or Plasma
CPT Code Information
80198 Therapeutic Drug Levels: Theophylline