Test Code THEO Theophylline (Aminophylline) LAB35
Test Method
Turbidimetric Inhibition Immunoassay; Beckman DXC600
Performance
Monday through Sunday
Routine: Typically completed within 4 hours after arrival at
the
testing site.
Expedite: Typically completed within 1 hour after
specimen
arrives at the testing site.
STAT: Typically completed within 30 minutes after specimen
arrives at the testing site.
Useful For
Assessing and adjusting dosage for optimal therapeutic level
Assessing toxicity
Specimen Requirement
0.5 mL serum or plasma is required.
CPT Code Information
80198 Therapeutic Drug Levels: Theophylline
Reference Values
Therapeutic: 8-20 mcg/mL
-
Critical Value: > 20 mcg/mL
LOINC Code Information
4049-3 Theophylline [Mass/Volume] In Serum Or Plasma
Additional Specimen Collection Information
Collect blood in a lithium heparin, green-top or red-top
tube.
Serum and plasma gel tubes are not acceptable.
- Suspected toxicity specimens are collected when symptoms
appear. - Acute therapy specimens are collected 30 minutes following
I.V.
loading dose and again at 4-8 hour intervals. - Peak specimens should be collected at least 2 hours
after
last dose for plain uncoated tablet and liquids; 4 hours after oral
dose for sustained release prducts.
Serum or plasma should be separated from contact with the
cells
within 2 hours of collection. Specimens not centrifuged within
4
hours of collection may be rejected. Refrigerate the specimen
if
unable to assay within 8 hours of collection. Samples with
>3+
lipemia must be cleared prior to analysis.