Test Code RMPSUM Monoclonal Protein Study, Random, Urine
Additional Codes
MAYO: RMPSU
EPIC: LAB5315
Reporting Name
Monoclonal Protein Study, Random, UUseful For
Diagnosing monoclonal gammopathies
Profile Information
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
RPEU | Protein Electrophoresis, Random, U | No | Yes |
RIFXU | Immunofixation, Random, U | No | Yes |
PTCON | Protein, Total, Random, U | No | Yes |
Testing Algorithm
The following algorithms are available:
Performing Laboratory

Specimen Type
UrineOrdering Guidance
The use of a random urine specimen is sufficient for identifying the presence or absence of a monoclonal immunoglobulin, but a 24-hour specimen is preferred for quantitating and monitoring the abnormality. See MPSU / Monoclonal Protein Study, 24 Hour, Urine.
Shipping Instructions
Refrigerate specimen during collection and send refrigerated.
Necessary Information
Specimen Required
Supplies:
-Urine Container, 60 mL (T313)
-Aliquot Tube, 5 mL (T465)
Submission Container/Tube: Plastic, 60-mL urine bottle and plastic, 5-mL tube
Specimen Volume: 50 mL
Collection Instructions:
1. Collect a random urine specimen.
2. Aliquot at least 25-mL of specimen into a plastic, 60-mL urine bottle and at least 1-mL of specimen into a plastic, 5-mL tube.
3. Label specimens appropriately (60-mL bottle for protein electrophoresis and 5-mL tube for protein, total).
Specimen Minimum Volume
25 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 14 days | |
Frozen | 5 days | ||
Ambient | 24 hours |
Special Instructions
Reference Values
PROTEIN, TOTAL:
No reference values apply to random urine.
ELECTROPHORESIS, PROTEIN
The following fractions, if present, will be reported as mg/dL:
Albumin
Alpha-1 globulin
Alpha-2 globulin
Beta globulin
Gamma globulin
Day(s) Performed
Protein, total: Monday through Sunday
Electrophoresis, protein; Immunofixation: Monday through Friday
Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84156
84166
86335
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
RMPSU | Monoclonal Protein Study, Random, U | In Process |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
PTCON | Protein, Total, Random, U | 2888-6 |
32526 | Immunofixation, Random, U | 74666-9 |
607975 | Albumin | 6942-7 |
607976 | Alpha-1 globulin | 9734-5 |
606979 | Immunofixation Flag, Random, U | No LOINC Needed |
607977 | Alpha-2 globulin | 38190-5 |
607978 | Beta globulin | 9744-4 |
607979 | Gamma globulin | 9745-1 |
33044 | A/G Ratio | 44293-9 |
33045 | M spike | 40661-1 |
33046 | M spike | 40661-1 |
33047 | Impression | 49299-1 |
Report Available
4 to 6 daysReject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Method Name
PTCON: Turbidimetry
RPEU: Agarose Gel Electrophoresis
RIFXU: Immunofixation
Secondary ID
60069Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.