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HelpTest Code MPSUM Monoclonal Protein Study, 24 Hour, Urine
Additional Codes
MAYO: MPSU
EPIC: LAB5288
Reporting Name
Monoclonal Protein Study, 24 Hr, UUseful For
Monitoring patients with monoclonal gammopathies using 24-hour urine specimens
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PTU | Protein, Total, 24 HR, U | Yes | Yes |
| PEU | Protein Electrophoresis, 24 Hr, U | No | Yes |
| IFXU | Immunofixation, 24 Hr, U | No | Yes |
Testing Algorithm
The following algorithms are available:
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineShipping Instructions
Refrigerate specimen during collection and send refrigerated.
Necessary Information
24-Hour volume is required.
Specimen Required
-Urine Container, 60 mL (T313)
-Aliquot Tube, 5 mL (T465)
Submission Container/Tube: Plastic, 60-mL urine bottle and plastic, 5-mL tube
Specimen Volume: 50 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Aliquot at least 25-mL specimen in plastic, 60-mL urine bottle and at least 1-mL of specimen in plastic, 5-mL tube.
3. Label specimens appropriately (60-mL bottle for protein electrophoresis and 5-mL tube for protein, total).
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.
Specimen Minimum Volume
25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 5 days | ||
| Ambient | 24 hours |
Special Instructions
Reference Values
PROTEIN, TOTAL
<229 mg/24 hours
Reference values have not been established for patients <18 years of age.
Reference value applies to 24-hour collection.
ELECTROPHORESIS, PROTEIN
The following fractions, if present, will be reported as mg/24 hours:
Albumin
Alpha-1 globulin
Alpha-2 globulin
Betaglobulin
Gamma globulin
Day(s) Performed
Protein, total: Monday through Sunday
Electrophoresis, protein; Immunofixation: Monday through Friday
Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84156
84166
86335
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MPSU | Monoclonal Protein Study, 24 Hr, U | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 82025 | Immunofixation, 24 Hr, U | 33042-3 |
| 607970 | Albumin | 6941-9 |
| TP2 | Total Protein, 24 HR, U | 2889-4 |
| TM23 | Collection Duration | 13362-9 |
| 607971 | Alpha-1 globulin | 6794-2 |
| 606980 | Immunofixation Flag, 24 Hr, U | No LOINC Needed |
| 607972 | Alpha-2 globulin | 6795-9 |
| VL21 | Urine Volume | 19153-6 |
| 607973 | Beta globulin | 94714-3 |
| 607974 | Gamma globulin | 94715-0 |
| 2833 | A/G Ratio | 44294-7 |
| 21446 | M spike | 42482-0 |
| 22307 | M spike | 42482-0 |
| 21447 | Impression | 32210-7 |
Report Available
4 to 6 daysReject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Method Name
PTU: Turbidimetry
PEU: Agarose Gel Electrophoresis
IFXU: Immunofixation
Secondary ID
8823Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.