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HelpTest Code HTGR Thyroglobulin, Tumor Marker Reflex, Serum
Useful For
Reporting of accurate thyroglobulin results, depending on the antithyroglobulin antibodies status of the patient
Accurate measurement of serum thyroglobulin in patients with known or suspected antithyroglobulin autoantibodies or possible heterophile antibodies
Testing Algorithm
This test begins with the analysis of thyroglobulin antibody by immunoassay. If the thyroglobulin antibody result is negative (<1.8 IU/mL), then thyroglobulin testing will be performed by immunoassay.
If the thyroglobulin antibody result is positive (≥1.8 IU/mL), then thyroglobulin testing will be performed by mass spectrometry.
Reporting Name
Thyroglobulin Reflex to MS or IASpecimen Type
Serum RedSpecimen Required
Patient Preparation: For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 7 days | |
| Frozen | 30 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Reference Values
Thyroglobulin Antibody: <1.8 IU/mL
Day(s) and Time(s) Performed
TGABR and HTGT:
Monday through Friday; 6 a.m.-12 a.m.
Saturday; 6 a.m.-6 p.m.
TGMS:
Monday through Friday; 4 p.m.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86800
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HTGR | Thyroglobulin Reflex to MS or IA | 56536-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TGABR | Thyroglobulin Antibody, S | 56536-6 |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| HTGT | Thyroglobulin, Tumor Marker, IA, S | No | No |
| TGMS | Thyroglobulin, Mass Spec., S | Yes | No |
Method Name
Immunoenzymatic Assay
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.