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Test Code HSCRP C-Reactive Protein, High Sensitivity LAB150

Important Note

Human anti-mouse antibodies (hama) may be present in samples from patients who have received immunotherapy or diagnostic procedures utilizing monoclonal antibodies or in individuals who have been regularly exposed to animals. Additionally, other heterophile antibodies, such as human anti-goat antibodies may be present in patient samples. Manufacturers formulate assays to minimize the effects of these antibodies; however careful evaluation of patient results must be done when patients are known to have such antibodies.

Test Method

Near Infrared Particle Immunoassay Rate; Beckman


Testing is performed Monday through Sunday.

Routine: Typically completed within 4 hours after the specimen
arrives at the testing site.

Expedite: Typically completed within 1.5 hours after the
specimen arrives at the testing site.

STAT: Typically completed within 1 hour after the specimen
arrives at the testing site.

Reference Values

Cardiovascular Risk Classification:

  • Low Risk: < 1.0 mg/L
  • Average Risk: 1.0-3.0 mg/L
  • High Risk: > 3.0 mg/L

Useful For

Measuring of very low levels of CRP (i.e. “normal
range” CRP) to stratify asymptomatic patients for
cardiovascular risk only. These low levels are not predictive of
other systemic inflammatory conditions usually associated with
elevated CRP or sedimentation rate. 

Specimen Requirement

0.5 mL of serum or plasma is required.

CPT Code Information

86141 C-reactive protein; highly sensitive

LOINC Code Information

30522-7 C Reactive Protein [Mass/Volume] In Serum Or Plasma By
High Sensitivity Method

Additional Specimen Collection Information

Collect blood in a lithium heparin, green-top or red-top tube.
PST and SST (gel tubes) are acceptable. Serum or plasma should be
separated from contact with the cells within 2 hours of collection.
Specimens not centrifuged within 4 hours of collection may be
rejected. Refrigerate the specimen if unable to assay within 8
hours of collection.